Guttman R
Biophys J. 1969 Mar;9(3):269-77. doi: 10.1016/S0006-3495(69)86385-X.
The temperature dependence of the oscillatory behavior of experimental and computed axons was compared. In the experimental study of space-clamped giant axons of the squid, small oscillations after a single threshold spike were measured using the double glucose gap over the temperature range 10 degrees -30 degrees C during treatment with three concentrations of external CaCl(2) solutions. Calcium concentration had little effect on frequency, as was found also by Huxley in his computations at 18.5 degrees C for a fiber at rest. The Q(10) both for the experimental and for the computed axon of FitzHugh was 2.25. The experimental measurements of the frequency of oscillations near threshold agree extremely well with the Hodgkin-Huxley calculations.
比较了实验性和计算性轴突振荡行为的温度依赖性。在对鱿鱼空间钳制的巨轴突进行的实验研究中,在10摄氏度至30摄氏度的温度范围内,使用双葡萄糖间隙测量了在三种浓度的外部氯化钙溶液处理期间单个阈下峰后的小振荡。钙浓度对频率影响很小,赫胥黎在18.5摄氏度对静息纤维的计算中也发现了这一点。实验性和菲茨休计算性轴突的Q(10)均为2.25。阈下振荡频率的实验测量结果与霍奇金-赫胥黎的计算结果极为吻合。