Waterloh E, Groth K H
Arzneimittelforschung. 1977;27(6B):1355-7.
Experience with 2-(2-hydroxyethoxy)-ethyl-N-(a,a,a-trifluoro-m-tolyl)-anthranilate (etofenamate; active principle of Rheumon Gel) in the treatment of traumatic injury to the ankle joint is reported. In testing the effect of the product, volumetric measurements were carried out using an apparatus that permits highly accurate assessment by a simple and rapid method of measurement. The studies were carried out as a double blind trial. The result of the study shows that compared with placebo gel the increase in volume due to haematoma is reduced statistically significantly more rapidly under treatment with etofenamate. No localized or generalized side effects were observed.
报道了2-(2-羟基乙氧基)乙基-N-(α,α,α-三氟间甲苯基)邻氨基苯甲酸酯（依托芬那酯；风湿凝胶的活性成分）治疗踝关节创伤性损伤的经验。在测试该产品的效果时，使用了一种通过简单快速的测量方法就能进行高精度评估的仪器进行体积测量。这些研究以双盲试验的方式进行。研究结果表明，与安慰剂凝胶相比，依托芬那酯治疗下血肿导致的体积增加在统计学上显著更快地减少。未观察到局部或全身性副作用。
