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冠状动脉疾病中的肝素中和活性(HNA)与抗凝血酶III

Heparin neutralizing activity (HNA) and antithrombin III in coronary artery disease.

作者信息

Cella G, Russo R

出版信息

Thromb Haemost. 1977 Oct 31;38(3):696-700.

PMID:579515
Abstract

Plasma from 14 patients with severe and diffuse coronary atherosclerosis has been compared with that obtained from a normal control group. While a decreased heparin-thrombin clotting time was demonstrated in the patient group, suggesting an increased level of circulating platelet factor 4, there was no significant alteration in plasma antithrombin III level. These results do not support a recent suggestion of a mild chronic intravascular coagulation in atherosclerosis.

摘要

对14例患有严重弥漫性冠状动脉粥样硬化患者的血浆与正常对照组的血浆进行了比较。虽然在患者组中发现肝素 - 凝血酶凝血时间缩短,提示循环血小板因子4水平升高,但血浆抗凝血酶III水平无明显变化。这些结果不支持最近关于动脉粥样硬化中存在轻度慢性血管内凝血的观点。

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引用本文的文献

1
Changes in the heparin neutralising activity of platelet poor plasma after immunisation.免疫后血小板缺乏血浆中肝素中和活性的变化。
J Clin Pathol. 1979 Nov;32(11):1152-4. doi: 10.1136/jcp.32.11.1152.