Hofstädter F, Aigner F, Zechmann W
Wien Klin Wochenschr. 1978 Apr 14;90(8):258-62.
A series of 1004 goitres removed surgically before (1959) and after (1970, 1975) the introduction of the iodine prophylaxis reveals an impressive increase in lymphocytic infiltration of the thyroid gland parenchyma. So-called focal lymphocytic thyroiditis is closely associated with the functional state of the organ. Furthermore, there is an increase in focal thyroiditis, especially in younger persons, after the introduction of iodine prophylaxis. Autoantibodies or clinical signs of inflammation were not found in these cases. Focal lymphocytic thyroiditis is seen as the expression of a regulatory function of the immunological system over the thyroid gland.
在引入碘预防措施之前（1959年）以及之后（1970年、1975年）通过手术切除的1004例甲状腺肿显示，甲状腺实质的淋巴细胞浸润显著增加。所谓的局灶性淋巴细胞性甲状腺炎与该器官的功能状态密切相关。此外，引入碘预防措施后，局灶性甲状腺炎有所增加，尤其是在年轻人中。在这些病例中未发现自身抗体或炎症的临床体征。局灶性淋巴细胞性甲状腺炎被视为免疫系统对甲状腺调节功能的一种表现。
