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高眼压症。一项15年的随访研究。

Ocular hypertension. A 15-year follow-up.

作者信息

Sørensen P N, Nielsen N V, Nørskov K

出版信息

Acta Ophthalmol (Copenh). 1978 Jun;56(3):363-72. doi: 10.1111/j.1755-3768.1978.tb05689.x.

DOI:10.1111/j.1755-3768.1978.tb05689.x
PMID:581127
Abstract

A group of 55 subjects with ocular hypertension were followed-up after 15 years. They were detected at a glaucoma screening on the island of Falster between 2031 volunteer blood donors, and they had an applanation pressure of greater than or equal to 20 mmHg in one or both eyes. All the subjects were traced. Nine have died, all from general causes, and one of the deceased subjects was treated for simple glaucoma. Of the remaining 46 living subjects, 3 developed glaucomatous visual field defects despite treatment. In another 4 subjects anti-glaucoma treatment was felt to be indicated. Of the non-treated 39 living subjects, 20 had a decreased applanation pressure, well below 20 mmHg, and 19 had an unaltered applanation pressure. We found that neither the common blood groups nor a water provocative test performed in 1962 were of any help in predicting glaucomatous visual field defects. Central corneal thickness measurements performed in 1977 could not allocate the subjects to the groups simple glaucoma, applanation pressure greater than 20 mmHg or less than or equal to 20 mmHg.

摘要

一组55名高眼压患者在15年后接受了随访。他们是在法尔斯特岛对2031名自愿献血者进行青光眼筛查时被检测出来的,他们一只或两只眼睛的压平眼压大于或等于20毫米汞柱。所有受试者都被追踪到了。9人已经死亡,均死于一般原因,其中一名已故受试者曾接受过单纯性青光眼治疗。在其余46名在世的受试者中,3人尽管接受了治疗仍出现了青光眼性视野缺损。另有4名受试者被认为需要进行抗青光眼治疗。在39名未接受治疗的在世受试者中,20人的压平眼压下降,远低于20毫米汞柱,19人的压平眼压未改变。我们发现,常见血型以及1962年进行的水激发试验对预测青光眼性视野缺损均无帮助。1977年进行的中央角膜厚度测量无法将受试者分为单纯性青光眼组、压平眼压大于20毫米汞柱组或小于或等于20毫米汞柱组。

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引用本文的文献

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Combined exfoliation and pigment dispersion: an overlap syndrome.联合性剥脱与色素播散:一种重叠综合征。
Trans Am Ophthalmol Soc. 1999;97:297-314; discussion 314-21.
2
Does medical treatment of mild intraocular hypertension prevent glaucoma?轻度眼压升高的药物治疗能否预防青光眼?
Eur J Epidemiol. 1997 Jan;13(1):19-23. doi: 10.1023/a:1007324907818.
3
The optic disc in glaucoma. IV: Optic disc evaluation in the ocular hypertensive patient.青光眼视盘。IV:高眼压症患者的视盘评估。
Br J Ophthalmol. 1980 Apr;64(4):232-9. doi: 10.1136/bjo.64.4.232.
4
The prevalence of glaucoma.青光眼的患病率。
Br J Ophthalmol. 1981 Jan;65(1):46-9. doi: 10.1136/bjo.65.1.46.
5
Ocular hypertension and posture.高眼压与姿势。
Br J Ophthalmol. 1983 Jun;67(6):362-6. doi: 10.1136/bjo.67.6.362.
6
Timolol treatment prevents or delays glaucomatous visual field loss in individuals with ocular hypertension: a five-year, randomized, double-masked, clinical trial.噻吗洛尔治疗可预防或延缓高眼压症患者的青光眼性视野缺损:一项为期五年的随机双盲临床试验。
Trans Am Ophthalmol Soc. 1989;87:598-618.
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The pattern electroretinogram in glaucoma and ocular hypertension.青光眼和高眼压症中的图形视网膜电图
Br J Ophthalmol. 1992 Jul;76(7):387-94. doi: 10.1136/bjo.76.7.387.