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英国婴儿高钠血症脱水发病率的下降

The declining incidence of infantile hypernatremic dehydration in Great Britain.

作者信息

Davies D P, Ansari B M, Mandal B K

出版信息

Am J Dis Child. 1979 Feb;133(2):148-50. doi: 10.1001/archpedi.1979.02130020038007.

DOI:10.1001/archpedi.1979.02130020038007
PMID:581718
Abstract

The feeding habits of 70 infants under 6 months old hospitalized with acute gastroenteritis were studied to determine whether current efforts to discourage high-solute feeding were having an effect on the incidence of hypernatremic dehydration. Fifteen infants (21%) were fed modified (low-solute) milks and 55 (79%) unmodified (high-solute) milks. Of 47 infants under 3 months old, 15 (32%) had commenced mixed feeding. Plasma sodium level was estimated in 60 infants. Mean values in the modified and unmodified groups were the same, at 137 mEq/liter. Only one infant was hypernatremic (sodium level, 152 m/eq/liter). Osmolalities of 65 samples of milk were measured to provide a measure of milk concentration. Only ten (16%) exceeded by more than 25% that recommended by the manufacturers. Twenty-two (34%) were less than 75% of the recommended concentrations. These improved feeding practices have probably contributed largely to the very low incidence of hypernatremia by preventing dangerously high solute intakes at a time of particular vulnerability.

摘要

对70名因急性肠胃炎住院的6个月以下婴儿的喂养习惯进行了研究,以确定当前劝阻高溶质喂养的措施是否对高钠血症脱水的发生率产生影响。15名婴儿(21%)喂养的是改良(低溶质)牛奶,55名婴儿(79%)喂养的是未改良(高溶质)牛奶。在47名3个月以下的婴儿中,有15名(32%)开始了混合喂养。对60名婴儿的血浆钠水平进行了评估。改良组和未改良组的平均值相同,为137毫当量/升。只有一名婴儿出现高钠血症(钠水平为152毫当量/升)。对65份牛奶样本的渗透压进行了测量,以衡量牛奶浓度。只有10份(16%)超过制造商推荐值25%以上。22份(34%)低于推荐浓度的75%。这些改进的喂养方式可能通过在特别易受影响的时期防止危险的高溶质摄入,在很大程度上导致了极低的高钠血症发生率。

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