Kerrebijn K F, Degenhart H J, Hammers A
Arch Dis Child. 1976 Apr;51(4):252-8. doi: 10.1136/adc.51.4.252.
This study was concerned with the correlation between skin test, bronchial provocation test, and histamine release from leucocytes and the serum level of total and allergen-specific IgE in patients atopic to house-dust mite allergen (Dermatophagiodes pteronyssinus) as measured by an intracutaneous skin test. It is concluded that, assuming a positive provocation test to be evidence of allergy, estimation of the allergen-specific IgE concentration in the serum will not offer any major advantages over the intradermal skin test in determining the clinical significance of house-dust mite allergy.
本研究关注皮内皮肤试验检测的对屋尘螨变应原(粉尘螨)过敏患者的皮肤试验、支气管激发试验、白细胞组胺释放与总IgE及变应原特异性IgE血清水平之间的相关性。得出的结论是,假设激发试验阳性为过敏证据,在确定屋尘螨过敏的临床意义方面,血清变应原特异性IgE浓度的测定相比皮内皮肤试验并无任何显著优势。