Butler M J, Britton B J, Wood W G, Mainwaring-Burton R, Irving M H
Br J Surg. 1977 Nov;64(11):786-90. doi: 10.1002/bjs.1800641109.
Plasma catecholamines have been measured before, during and after operation in 40 patients undergoing elective major abdominal surgery and in 12 patients during open heart surgery. Plasma concentrations did not increase during abdominal surgery and showed only small increases during cardiopulmonary bypass. It appears that it is not possible to assess individual intra-operative sympatho-adrenal responses to surgical trauma by measurement of plasma catecholamine concentrations because of the efficiency of catecholamine uptake mechanisms.
对40例接受择期腹部大手术的患者以及12例接受心脏直视手术的患者，在手术前、手术期间及手术后测定了血浆儿茶酚胺水平。腹部手术期间血浆浓度未升高，体外循环期间仅出现小幅升高。由于儿茶酚胺摄取机制的高效性，通过测定血浆儿茶酚胺浓度来评估个体术中对手术创伤的交感 - 肾上腺反应似乎是不可能的。
