Florek M, Karolak S
Eur J Pediatr. 1977 Nov 4;126(4):275-82. doi: 10.1007/BF00477054.
The I.Q. of 129 patients with PMD-D and 27 patients suffering from Werdnig-Hoffmann disease were estimated. Among the patients with PMD-D there was one group without any complicating factors and 3 other groups with additional factors that might influence the intelligence level. Comparing mean values and distribution of I.Q. for all these groups, one can conclude that, besides additional unfavourable pathological and environmental factors in all cases, PMD-D itself causes a small decrease of the I.Q. by about 1 SD. The frequent changes of the EEG record in these patients could reflect involvement of the CNS by the pathological process.
对129例佩梅病-弥漫性（PMD-D）患者和27例患有韦尼克-霍夫曼病的患者的智商进行了评估。在PMD-D患者中，有一组没有任何复杂因素，另外3组有可能影响智力水平的其他因素。比较所有这些组的智商平均值和分布情况，可以得出结论，除了所有病例中额外的不利病理和环境因素外，PMD-D本身会使智商小幅下降约1个标准差。这些患者脑电图记录的频繁变化可能反映了病理过程对中枢神经系统的累及。
