Barondes S H, Cohen H D
Science. 1966 Feb 4;151(3710):594-5. doi: 10.1126/science.151.3710.594.
Mice injected bitemporally with puromycin 5 hours before training learned to escape or to avoid shock by choosing the correct limb of a Y-maze. When retested 15 minutes after training they had normal retention. In the ensuing 2(3/4) hours the animals injected with puromycin, unlike the controls, showed a progressive decrease of savings to less than 7 percent.
在训练前5小时双侧注射嘌呤霉素的小鼠,通过选择Y型迷宫的正确分支学会逃避或避免电击。训练后15分钟重新测试时,它们的记忆保持正常。在随后的2(3/4)小时内,注射嘌呤霉素的动物与对照组不同,节省率逐渐下降至不到7%。