Fuve R M, Alouf J E, Delaunay A, Raynaud M
J Bacteriol. 1966 Oct;92(4):1150-3. doi: 10.1128/jb.92.4.1150-1153.1966.
Fauve, Robert M. (Institut Pasteur, Garches (Hauts de Seine), France), Joseph E. Alouf, Albert Delaunay, and Marcel Raynaud. Cytotoxic effects in vitro of highly purified streptolysin O on mouse macrophages cultured in a serum-free medium. J. Bacteriol. 92:1150-1153. 1966.-After the addition of highly purified streptolysin O to mouse macrophages cultured in medium 199 containing albumin, the following cellular alterations were observed. The disappearance of the stellate shape of the cells and the formation of bleb-like vesicles extruding from the cytoplasmic membrane occurred within a few minutes. Later, massive degranulation and formation of cytoplasmic vesicles were followed by cell death.
福夫，罗伯特·M.（法国上塞纳省加歇巴斯德研究所），约瑟夫·E.阿洛夫，阿尔贝·德洛奈，以及马塞尔·雷诺。高纯度链球菌溶血素O在无血清培养基中培养的小鼠巨噬细胞上的体外细胞毒性作用。《细菌学杂志》92:1150 - 1153。1966年。——在向含有白蛋白的199培养基中培养的小鼠巨噬细胞添加高纯度链球菌溶血素O后，观察到以下细胞变化。细胞的星状形态消失，几分钟内从细胞质膜挤出形成泡状小泡。随后，大量脱颗粒和细胞质小泡形成，接着细胞死亡。
