环丁砜的急性毒性和皮肤刺激性
Acute toxicity and skin irritant properties of sulfolane.
作者信息
Brown V K, Ferrigan L W, Stevenson D E
出版信息
Br J Ind Med. 1966 Oct;23(4):302-4. doi: 10.1136/oem.23.4.302.
Abstract
Sulfolane is a useful industrial solvent. The oral LD values were: rats, 1·7 to 2·7 g./kg.; mice, 1·9 to 2·5 g./kg., all deaths taking place within 24 hours. Rats showed no effects after 3·8 g./kg. had been applied to the skin. The compound did not irritate or sensitize the skins of guinea-pigs or rabbits and, undiluted, was almost without action on the eyes of rabbits.
摘要
环丁砜是一种有用的工业溶剂。经口半数致死量值为：大鼠，1.7至2.7克/千克；小鼠，1.9至2.5克/千克，所有死亡均在24小时内发生。给大鼠皮肤涂抹3.8克/千克后未出现任何影响。该化合物对豚鼠或兔子的皮肤无刺激或致敏作用，未稀释时对兔子眼睛几乎无作用。
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