Harder F
Langenbecks Arch Chir. 1977 Nov;345:107-10. doi: 10.1007/BF01305455.
Combined surgical, radiotherapeutic, and sometimes chemotherapeutic treatment of early stages of operable mammary cancer results in 5-year survival without recurrence in a similar percentage of cases as modified radical mastectomy does. This is demonstrated with 1296 patients of two French and one American groups using comparable indication and therapeutic principles. No controlled studies of long-term results using these principles are thus far available. Preliminary results of a Swiss adjuvant polychemotherapy study after mastectomy show a significant favorable effect only in patients with negative axillary lymph nodes.
对可手术乳腺癌早期阶段采用手术、放疗，有时联合化疗的综合治疗，其5年无复发生存率与改良根治性乳房切除术相似。两个法国组和一个美国组的1296例患者采用了可比的适应症和治疗原则，证实了这一点。迄今为止，尚无使用这些原则的长期结果的对照研究。瑞士一项乳房切除术后辅助多药化疗研究的初步结果显示，仅对腋窝淋巴结阴性的患者有显著的有利影响。
