大鼠小肠在体外对丙酸盐的转运
Transfer of propionate by rat small intestine in vitro.
作者信息
Barry R J, Jackson M J, Smyth D H
出版信息
J Physiol. 1966 Jan;182(1):150-63. doi: 10.1113/jphysiol.1966.sp007815.
Abstract
- The transfer of propionate by sacs of rat everted intestine has been investigated in relation to a number of physico-chemical factors which affect movement of weak electrolytes.2. Neither the observed movement nor the distribution of propionate can be accounted for by the theory of non-ionic diffusion or by modifications of it, such as the microclimate hypothesis or partial permeability to ions.3. It is not possible to account for the observed propionate movement by the electrical potential across the gut or by solvent drag.4. The most satisfactory explanation for the observations is a transfer process in the gut for volatile fatty acids, and some features of this are discussed.
摘要
- 已针对影响弱电解质移动的若干物理化学因素，对大鼠外翻肠囊转运丙酸盐的情况进行了研究。2. 无论是观察到的丙酸盐移动还是其分布，都无法用非离子扩散理论或对其的修正理论（如微气候假说或对离子的部分通透性）来解释。3. 无法通过肠道两侧的电势或溶剂拖曳来解释观察到的丙酸盐移动。4. 对这些观察结果最令人满意的解释是肠道中存在挥发性脂肪酸的转运过程，并对其一些特征进行了讨论。
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