Cummins J E, Blomquist J C, Rusch H P
Science. 1966 Dec 9;154(3754):1343-4. doi: 10.1126/science.154.3754.1343.
The relationship between protein synthesis and mitosis was studied in Physarum polycephalum, a plasmodial slime mold whose nuclear divisions are synchronous. Results of studies with actidione (cycloheximide), an inhibitor of protein synthesis, indicated that the essential structural proteins for mitosis and nuclear reconstruction were completed prior to the dissolution of the nucleolus in prophase. Proteins that determine the duration of the transition from metaphase to nuclear reconstruction were synthesized from late prophase to prometaphase. It is proposed that these proteins are concerned with the transformation of chemical energy into the mechanical work of mitosis.
在多头绒泡菌（一种核分裂同步的多核变形虫状粘菌）中研究了蛋白质合成与有丝分裂之间的关系。用蛋白质合成抑制剂放线菌酮（环己酰亚胺）进行的研究结果表明，有丝分裂和核重建所需的基本结构蛋白在前期核仁溶解之前就已完成合成。决定从中期到核重建转变持续时间的蛋白质是在前期后期到前中期合成的。有人提出，这些蛋白质与将化学能转化为有丝分裂的机械功有关。
