Blomstedt B, Jacobsson S I
Acta Chir Scand. 1977;143(5):259-63.
The physical properties of polyglactin 910 (Vicryl) have been studied experimentally and clinically and compared with other synthetic and natural suture materials. Polyglactin 910 has a relatively high fluid absorption capacity but a low capillary capacity. The tensile strength is high and well comparable with, or superior, to other synthetic non-absorbable suture materials commonly used. The elongation at break is moderate. No unfavourable wound reaction to the suture material has been registered. The material has not increased the expected frequency of wound infections. The follow up of laparotomized patients 12-18 months after the operation showed a very low frequency of wound hernia. Neither was any recurrence noticed after repair of inguinal hernia. No clinical signs of leakage in the anastomoses of the gastrointestinal region was registrated. It is concluded that polyglactin 910 in a wide extent seems to be able to replace catgut and also non-absorbable suture materials when normal wound healing is to be expected.
已对聚乙醇酸910（薇乔）的物理特性进行了实验和临床研究，并与其他合成和天然缝合材料进行了比较。聚乙醇酸910具有相对较高的吸液能力，但毛细作用能力较低。其拉伸强度较高，与常用的其他合成非吸收性缝合材料相当，或更胜一筹。断裂伸长率适中。未记录到对缝合材料的不良伤口反应。该材料并未增加预期的伤口感染发生率。对接受剖腹手术的患者术后12 - 18个月的随访显示，伤口疝的发生率极低。腹股沟疝修补术后也未发现复发情况。未记录到胃肠道区域吻合口有渗漏的临床迹象。结论是，在预期正常伤口愈合的情况下，聚乙醇酸910在很大程度上似乎能够替代肠线以及非吸收性缝合材料。
