利用从小鼠肥大细胞释放的3H 5-羟色胺作为介质释放的一种检测方法。
The use of 3H serotonin release from mast cells of the mouse as an assay for mediator liberation.
作者信息
Otsuki J A, Grassick R, Seymour D, Kind L S
出版信息
Immunol Commun. 1976;5(1-2):27-39. doi: 10.3109/08820137609020610.
PMID:59700
Abstract
The release of 3H 5-HT from murine mast cells is shown to be a simple reproducible method for studying the activation of such cells by various agents. 3H-serotonin was taken up by peritoneal cell suspensions in vitro and was released by antigen, Concanavalin A, Forssman antiserum, anti-mouse immunoglobulin, or a polypeptide antibiotic, Cinnamycin.
摘要
从小鼠肥大细胞中释放3H 5-羟色胺是一种用于研究各种试剂激活此类细胞的简单且可重复的方法。3H-血清素在体外被腹膜细胞悬液摄取，并可被抗原、刀豆球蛋白A、福斯曼抗血清、抗小鼠免疫球蛋白或一种多肽抗生素肉桂霉素释放出来。
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