Schneider M D, Ehrlich R, Yamashiroya H M, Miller S
Appl Microbiol. 1966 Sep;14(5):767-8. doi: 10.1128/am.14.5.767-768.1966.
Experimental data are presented which demonstrate that the complement-fixing antibody response in individual mice can be used for quantitative assay of Coxiella burnetii. The method allows the replacement of a single guinea pig with a single mouse, thus resulting in considerable savings in caging requirements and animal costs.
实验数据表明,个体小鼠的补体结合抗体反应可用于伯氏考克斯体的定量检测。该方法用一只小鼠替代了一只豚鼠,从而在笼舍需求和动物成本方面节省了大量开支。