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脂肪族含氮化合物的抑菌、抑真菌和抑藻活性。

Bacteriostatic, fungistatic, and algistatic activity of fatty nitrogen compounds.

作者信息

Hueck H J, Adema D M, Wiegmann J R

出版信息

Appl Microbiol. 1966 May;14(3):308-19. doi: 10.1128/am.14.3.308-319.1966.

Abstract

A total of 164 fatty nitrogen compounds, consisting of quaternary ammonium compounds, alkylamines, N-alkyl-1, 3-propylene diamines, substituted amino hydroxystearonitriles, substituted amino hydroxystearyl amines, and nitrogen-containing surfactants, were screened for bacteriostatic, fungistatic, and algistatic activity. The most active compounds were dodecylamine and dodecylamine acetate. A number of compounds were very active against gram-negative bacteria. Most of the surfactants were virtually nontoxic to all of the test organisms.

摘要

共筛选了164种脂肪族含氮化合物,包括季铵化合物、烷基胺、N-烷基-1,3-丙二胺、取代氨基羟基硬脂腈、取代氨基羟基硬脂胺和含氮表面活性剂,以检测其抑菌、抑真菌和抑藻活性。活性最高的化合物是十二烷基胺和十二烷基胺乙酸盐。许多化合物对革兰氏阴性菌具有很强的活性。大多数表面活性剂对所有受试生物几乎无毒。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/afc4/546700/202cb623eb54/applmicro00229-0009-a.jpg

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