Hueck H J, Adema D M, Wiegmann J R
Appl Microbiol. 1966 May;14(3):308-19. doi: 10.1128/am.14.3.308-319.1966.
A total of 164 fatty nitrogen compounds, consisting of quaternary ammonium compounds, alkylamines, N-alkyl-1, 3-propylene diamines, substituted amino hydroxystearonitriles, substituted amino hydroxystearyl amines, and nitrogen-containing surfactants, were screened for bacteriostatic, fungistatic, and algistatic activity. The most active compounds were dodecylamine and dodecylamine acetate. A number of compounds were very active against gram-negative bacteria. Most of the surfactants were virtually nontoxic to all of the test organisms.
共筛选了164种脂肪族含氮化合物,包括季铵化合物、烷基胺、N-烷基-1,3-丙二胺、取代氨基羟基硬脂腈、取代氨基羟基硬脂胺和含氮表面活性剂,以检测其抑菌、抑真菌和抑藻活性。活性最高的化合物是十二烷基胺和十二烷基胺乙酸盐。许多化合物对革兰氏阴性菌具有很强的活性。大多数表面活性剂对所有受试生物几乎无毒。