一些长链脂肪酸N-取代酰胺的抗菌活性。
Antimicrobial activity of some N-substituted amides of long-chain fatty acids.
作者信息
Novak A F, Solar J M, Mod R R, Magne F C, Skau E L
出版信息
Appl Microbiol. 1969 Dec;18(6):1050-6. doi: 10.1128/am.18.6.1050-1056.1969.
Abstract
Seventy-three N,N-disubstituted amides of long-chain, principally C(18), fatty acids were screened for antimicrobial activity against bacteria, yeasts, and molds. Amides containing an epoxy group exhibit a broad spectrum of antimicrobial activity which is further enhanced by unsaturation. Mono-unsaturation alone does not contribute a broad level of activity to the N,N-disubstituted amides of the C(18) fatty acids.
摘要
对73种主要为C(18)长链脂肪酸的N,N-二取代酰胺进行了抗细菌、酵母和霉菌的抗菌活性筛选。含有环氧基的酰胺表现出广谱抗菌活性，这种活性会因不饱和键而进一步增强。仅单不饱和键不会为C(18)脂肪酸的N,N-二取代酰胺带来广泛的活性水平。
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