Adami H O, Rimsten A, Stenkvist B, Vegelius J
Br J Cancer. 1977 Dec;36(6):787-92. doi: 10.1038/bjc.1977.263.
A number of recent studies have shown an association between breast-cancer risk and height, weight and dietary habits, especially fat consumption. In the present study, height and weight were determined for 179 consecutive, unselected, breast-cancer patients and age-matched controls selected from a computerized population register. Height and weight for these two groups were compared, including two different indices for overweight (Quetelet's index and Broca's index). Comparisons were repeated after subdivision into pre- and postmenopausal women. In all calculations, the mean values of patients and controls were very similar and without significant difference. It therefore seems improbable that increased height and weight or obesity constitute risk factors for breast cancer. Earlier studies may have shown differences as the result of selection mechanisms not present in this study.
近期的多项研究表明，乳腺癌风险与身高、体重及饮食习惯，尤其是脂肪摄入量之间存在关联。在本研究中，从计算机化人口登记册中选取了179名连续的、未经挑选的乳腺癌患者以及年龄匹配的对照组，测定了他们的身高和体重。对这两组的身高和体重进行了比较，包括两种不同的超重指标（奎特莱特指数和布罗卡指数）。在将两组再细分为绝经前和绝经后女性后，重复进行了比较。在所有计算中，患者和对照组的平均值非常相似，无显著差异。因此，身高增加、体重增加或肥胖似乎不太可能构成乳腺癌的风险因素。早期的研究可能由于本研究中不存在的选择机制而显示出差异。
