Lebedev K A, Kaulen D R, Khorobrykh V V, D'iakov G N, Simonova A V
Biull Eksp Biol Med. 1977 Dec;84(12):712-4.
The action of antitumour sera on the adhesive properties of the L-cells and the cells of Ehrlich's ascitic carcinoma. It was shown that after the treatment with immune sera the tumour cells lost their capacity to form rosettes with sheep red blood cells, to adhere to plastics and glass; when administered into the mouse organism these cells were worse retained in the lungs, spleen and the liver. The data obtained indicated that the antibodies could play a significant role in the tumour cell metastasis.
抗肿瘤血清对L细胞和艾氏腹水癌细胞黏附特性的作用。结果表明,经免疫血清处理后,肿瘤细胞失去了与绵羊红细胞形成玫瑰花结、黏附于塑料和玻璃的能力;将这些细胞注入小鼠体内后,它们在肺、脾和肝脏中的留存情况变差。所获得的数据表明,抗体可能在肿瘤细胞转移中发挥重要作用。