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[用免疫血清处理的肿瘤细胞的迁移能力]

[Migration capacity of tumor cells treated with immune sera].

作者信息

Lebedev K A, Kaulen D R, Khorobrykh V V, D'iakov G N, Simonova A V

出版信息

Biull Eksp Biol Med. 1977 Dec;84(12):712-4.

PMID:597608
Abstract

The action of antitumour sera on the adhesive properties of the L-cells and the cells of Ehrlich's ascitic carcinoma. It was shown that after the treatment with immune sera the tumour cells lost their capacity to form rosettes with sheep red blood cells, to adhere to plastics and glass; when administered into the mouse organism these cells were worse retained in the lungs, spleen and the liver. The data obtained indicated that the antibodies could play a significant role in the tumour cell metastasis.

摘要

抗肿瘤血清对L细胞和艾氏腹水癌细胞黏附特性的作用。结果表明,经免疫血清处理后,肿瘤细胞失去了与绵羊红细胞形成玫瑰花结、黏附于塑料和玻璃的能力;将这些细胞注入小鼠体内后,它们在肺、脾和肝脏中的留存情况变差。所获得的数据表明,抗体可能在肿瘤细胞转移中发挥重要作用。

相似文献

1
[Migration capacity of tumor cells treated with immune sera].[用免疫血清处理的肿瘤细胞的迁移能力]
Biull Eksp Biol Med. 1977 Dec;84(12):712-4.
2
[The effect of ascitic fluid globulins on the growth of leukemia P388/DOX and Ehrlich's carcinoma in mice].[腹水球蛋白对小鼠白血病P388/DOX及艾氏癌生长的影响]
Biull Eksp Biol Med. 1992 Nov;114(11):518-9.
3
[Inhibition of the growth of Ehrlich transplantable carcinoma in mice by antichorionic immune serum].[抗绒毛膜免疫血清对小鼠艾氏移植癌生长的抑制作用]
Vopr Onkol. 1983;29(2):62-4.
4
[Action of embryonic thymus and liver cells on the development of the ascitic form of Ehrlich's carcinoma].
Ontogenez. 1978;9(6):632-5.
5
[The effect of ascitic fluid on the growth of Ehrlich tumor and Lewis carcinoma].[腹水对艾氏腹水癌和刘易斯肺癌生长的影响]
Biull Eksp Biol Med. 1992 Jul;114(8):191-3.
6
Augmentation of in vivo antitumour activity of xenogeneic antiserum by autotransplanted normal spleen cells in mice.自体移植正常脾细胞增强小鼠体内异种抗血清的抗肿瘤活性
Eur J Cancer (1965). 1981 Jan;17(1):77-80.
7
[Effect of mouse interferons on the development of Ehrlich ascitic carcinoma].
Biull Eksp Biol Med. 1980 Mar;89(3):330-2.
8
[The modelling of the growth of Ehrlich carcinoma and teratoma T-36 with ascitic fluid and tumor-cell dialysate].[艾氏腹水癌和畸胎瘤T-36伴腹水及肿瘤细胞透析液生长的模型构建]
Biull Eksp Biol Med. 1992 Jul;114(8):193-5.
9
[The characteristics of Ehrlich carcinoma recurrence and metastasis].[艾氏腹水癌复发与转移的特征]
Biull Eksp Biol Med. 1992 Dec;114(12):652-4.
10
[Effect of the nucleic acids from the ascitic fluid of Ehrlich's tumor on its transplantability].[艾氏腹水瘤腹水核酸对其移植性的影响]
Vopr Onkol. 1981;27(12):56-9.