脑脊液免疫球蛋白和补体在脑膜炎球菌性脑膜炎中的情况
Cerebrospinal fluid immunoglobulins and complement in meningococcal meningitis.
作者信息
Whittle H C, Greenwood B M
出版信息
J Clin Pathol. 1977 Aug;30(8):720-2. doi: 10.1136/jcp.30.8.720.
Abstract
Cerebrospinal fluid (CSF) immunoglobulins (IgA, IgG, IgM) were measured in 107 patients with meningococcal meningitis. Levels were correlated significantly with CSF total protein, and both CSF immunoglobulin and protein increased with age. C3 was measured in the CSF of 38 patients and was also closely correlated with the CSF protein level. C3 breakdown products were found in all six CSFs tested. The CSF immunoglobulin and complement were thought to have leaked from the plasma due to inflammation of the meninges and had little value in diagnosis or prognosis.
摘要
对107例脑膜炎球菌性脑膜炎患者的脑脊液（CSF）免疫球蛋白（IgA、IgG、IgM）进行了检测。其水平与CSF总蛋白显著相关，且CSF免疫球蛋白和蛋白均随年龄增长而升高。对38例患者的CSF进行了C3检测，其也与CSF蛋白水平密切相关。在所检测的全部6份CSF中均发现了C3裂解产物。CSF免疫球蛋白和补体被认为是由于脑膜炎症从血浆中漏出的，对诊断或预后价值不大。
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