血清IgM抗体与甲型流感感染。
Serum IgM antibody and influenza A infection.
作者信息
Buchner Y I, Heath R B, Collins J V, Pattison J R
出版信息
J Clin Pathol. 1977 Aug;30(8):723-7. doi: 10.1136/jcp.30.8.723.
Abstract
Sucrose density gradient ultracentrifugation followed by haemagglutination inhibition for demonstrating specific influenza IgM was evaluated as a means of confirming recent infection with influenza A viruses. Specific IgM antibodies were found in at least one serum obtained from 83% of patients with proven recent infection with influenza A viruses but in none of the sera from 21 individuals without evidence of infection. Influenza IgM antibodies persisted for up to 112 days after infection. The relative merits of detecting specific IgM and complement fixing antibodies for diagnostic purposes are discussed.
摘要
通过蔗糖密度梯度超速离心法结合血凝抑制试验来检测特异性流感IgM，以此作为确认近期甲型流感病毒感染的一种方法进行了评估。在确诊近期感染甲型流感病毒的患者中，83%的患者至少一份血清中发现了特异性IgM抗体，而在21名无感染证据的个体的血清中均未发现。流感IgM抗体在感染后可持续长达112天。文中讨论了检测特异性IgM和补体结合抗体用于诊断目的的相对优点。
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本文引用的文献
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Formation of antibodies of different classes in influenzal infections.流感感染中不同类别抗体的形成。
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Immunoglobulin class of influenza antibodies investigated by radioimmunoassay (RIA).通过放射免疫测定法（RIA）研究的流感抗体的免疫球蛋白类别。
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Serum IgM and IgA responses in influenza A infections.甲型流感感染中的血清IgM和IgA反应。
J Clin Pathol. 1974 Mar;27(3):198-201. doi: 10.1136/jcp.27.3.198.
5
The detection of specific IgM antibodies following infection with rubella virus.风疹病毒感染后特异性IgM抗体的检测。
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6
Detection of antibodies of the IgM class in sera of patients recently infected with influenza viruses.在近期感染流感病毒患者血清中检测 IgM 类抗体。
J Clin Pathol. 1976 May;29(5):423-7. doi: 10.1136/jcp.29.5.423.
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