Pattison J R, Mace J E
J Clin Pathol. 1975 May;28(5):377-82. doi: 10.1136/jcp.28.5.377.
A gel filtration technique using Sephadex G-200 has been used for the detection of specific IgM in sera from (a) 45 cases of clinical rubella in which diagnostic rises of rubella haemagglutination-inhibiting (HAI) antibody could be demonstrated; (b) 70 cases with clinical evidence of rubella in which a rising titre could not be demonstrated because the first serum sample already had high titre HAI antibodies; and (c) 100 patients in whom rubella was not suspected. The results indicate that the high specificity and sensitivity of the method described make it an appropriate technique for use in the routine diagnosis of acquired rubella.
一种使用葡聚糖凝胶G - 200的凝胶过滤技术已被用于检测血清中的特异性IgM，这些血清来自：(a) 45例临床风疹病例，其中可证明风疹血凝抑制(HAI)抗体有诊断性升高；(b) 70例有风疹临床证据的病例，由于第一份血清样本已经有高滴度的HAI抗体，所以无法证明滴度上升；(c) 100例未怀疑患有风疹的患者。结果表明，所描述方法的高特异性和敏感性使其成为用于获得性风疹常规诊断的合适技术。
