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羧苄青霉素治疗慢性尿路感染的临床研究(作者译)

[Clinical study of carfecillin in chronic urinary tract infection (author's transl)].

作者信息

Hayahara N, Nishijima T, Maeda T, Oyama T, Matsumura T, Nishio S, Funai K, Sasaki S, Nakanishi J, Tsujita M, Kishimoto T, Maekawa M

出版信息

Jpn J Antibiot. 1977 Dec;30(12):993-8.

PMID:599660
Abstract
  1. Ten patients with chronic urinary tract infection by Pseudomonas aeruginosa or Proteus species were treated with carfecillin. Excellent response was seen in one case, fairly good in 5 cases and clinical effective rate was 60%. 2. The recurrence suppression effect of carfecillin was examined in two patients suffering from complicated urinary tract infection. In both cases, recurrence was not found when carfecillin was administered for a week after the effective pretreatment of carbenicillin, but found when administered for two weeks. 3. Side effects were observed in 3 cases (itching, tinnitus, diarrhea).
摘要
  1. 10例由铜绿假单胞菌或变形杆菌属引起慢性尿路感染的患者接受了羧苄青霉素苯酯治疗。1例效果极佳,5例效果较好,临床有效率为60%。2. 在2例复杂性尿路感染患者中检测了羧苄青霉素苯酯的复发抑制效果。在两例患者中,在羧苄西林有效预处理后给予羧苄青霉素苯酯一周时未发现复发,但给予两周时发现复发。3. 3例出现副作用(瘙痒、耳鸣、腹泻)。

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