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MOD-MEM癌症检测在患有非恶性疾病的对照人群中的临床评估。

Clinical assessment of the MOD-MEM cancer test in controls with non-malignant diseases.

作者信息

Pritchard J A, Moore J L, Sutherland W H, Joslin C A

出版信息

Br J Cancer. 1976 Jul;34(1):1-6. doi: 10.1038/bjc.1976.113.

DOI:10.1038/bjc.1976.113
PMID:60118
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2025130/
Abstract

A control series of 105 patients in hospital with non-malignant diseases was used in a limited clinical assessment of the MOD-MEM test. Twenty-seven positive results could be explained on the basis of destruction of nervous parenchyma, tissue necrosis, tuberculosis, malignant disease, etc. The remaining 13 unexplained positives showed a sex and age distribution in agreement with that predicted from cancer registration statistics if the MOD-MEM test detects cancer about 16 years before the clinical appearance of the disease.

摘要

在对MOD - MEM检测进行的有限临床评估中,选取了105名患有非恶性疾病的住院患者作为对照系列。27个阳性结果可基于神经实质破坏、组织坏死、结核病、恶性疾病等情况进行解释。其余13个无法解释的阳性结果显示出的性别和年龄分布,与癌症登记统计数据所预测的情况相符,前提是MOD - MEM检测能在疾病临床出现前约16年检测出癌症。

相似文献

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Clinical assessment of the MOD-MEM cancer test in controls with non-malignant diseases.MOD-MEM癌症检测在患有非恶性疾病的对照人群中的临床评估。
Br J Cancer. 1976 Jul;34(1):1-6. doi: 10.1038/bjc.1976.113.
2
The macrophage electrophoretic mobility (MEM) test--an investigation of its value as a routine laboratory test in the detection of malignant disease.巨噬细胞电泳迁移率(MEM)试验——对其作为检测恶性疾病常规实验室检查价值的一项研究。
Ann Clin Res. 1978 Apr;10(2):71-4.
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Macrophage electrophoretic mobility (MEM) test in malignant gynaecological diseases.妇科恶性疾病中的巨噬细胞电泳迁移率(MEM)检测
Arch Gynakol. 1976 Mar 5;220(3):191-8. doi: 10.1007/BF00667747.
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Macrophage electrophoretic mobility (MEM) with myelin basic protein.巨噬细胞电泳迁移率(MEM)与髓鞘碱性蛋白
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Reactivity of lymphocytes to basic proteins prepared from brain glioma and stomach cancer with MEM test.采用微量培养试验检测淋巴细胞对脑胶质瘤和胃癌制备的碱性蛋白的反应性。
Br J Cancer. 1981 Apr;43(4):532-6. doi: 10.1038/bjc.1981.76.
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Responses of cancer patients in the MEM test: not just a function of charge on basic proteins.癌症患者在MEM测试中的反应:不仅仅是碱性蛋白质电荷的函数。
Br J Cancer. 1976 Jul;34(1):7-13. doi: 10.1038/bjc.1976.114.
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The clinical assessment of cancer tests: a statistical approach to the prediction of "false positive" rates from controls.癌症检测的临床评估:一种从对照中预测“假阳性”率的统计方法。
Ann Clin Res. 1977 Apr;9(2):45-51.
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An assessment of the macrophage electrophoretic mobility test (MEM) in cancer diagnosis.巨噬细胞电泳迁移率试验(MEM)在癌症诊断中的评估。
J Clin Pathol. 1976 Jul;29(7):608-9. doi: 10.1136/jcp.29.7.608.
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Reactivity in the MEM-test of cancer patients' lymphocytes incubated with brain-derived preparations and extracts from malignant teratomas.癌症患者淋巴细胞与脑源性制剂及恶性畸胎瘤提取物共同孵育后的微量淋巴细胞毒试验反应性。
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Comparison between the macrophage electrophoretic mobility (MEM) and the fixed tanned erythrocyte electrophoretic mobility (FTEEM) tests in the detection of cancer.巨噬细胞电泳迁移率(MEM)检测与固定鞣酸红细胞电泳迁移率(FTEEM)检测在癌症检测中的比较。
Int J Cancer. 1978 Apr 15;21(4):413-7. doi: 10.1002/ijc.2910210403.

引用本文的文献

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Cell electrophoresis for diagnostic purposes. I. Diagnostic value of the electrophoretic mobility test (EMT) for the detection of gynaecological malignancies.用于诊断目的的细胞电泳。I. 电泳迁移率测试(EMT)在检测妇科恶性肿瘤中的诊断价值。
Br J Cancer. 1981 May;43(5):588-97. doi: 10.1038/bjc.1981.88.
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Effect of lymphocyte supernatants on the electrophoretic mobility of erythrocytes: significance in cancer diagnosis.淋巴细胞上清液对红细胞电泳迁移率的影响:在癌症诊断中的意义
Br J Cancer. 1978 Sep;38(3):401-10. doi: 10.1038/bjc.1978.221.
4
Lymphocyte response to antigen stimulation as measured by fluorescence polarization (SCM test).通过荧光偏振测量的淋巴细胞对抗原刺激的反应(SCM试验)。
Br J Cancer. 1978 Aug;38(2):339-43. doi: 10.1038/bjc.1978.208.
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Cellular immunity to encephalitogenic factor as measured by macrophage migration inhibition during tumour induction and growth.在肿瘤诱导和生长过程中,通过巨噬细胞迁移抑制来测定的对致脑炎因子的细胞免疫。
Br J Cancer. 1978 May;37(5):818-26. doi: 10.1038/bjc.1978.120.

本文引用的文献

1
Some biological properties of a highly active encephalitogenic factor isolated from human brain.从人脑中分离出的一种高活性致脑炎因子的某些生物学特性。
Lancet. 1963 Jul 6;2(7297):11-3. doi: 10.1016/s0140-6736(63)92533-9.
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Immunodiagnosis of cancer.癌症的免疫诊断
Br Med J. 1972 Sep 9;3(5827):641-2. doi: 10.1136/bmj.3.5827.641.
3
Technical aspects of the macrophage electrophoretic mobility (MEM) test for malignant disease.用于恶性疾病的巨噬细胞电泳迁移率(MEM)检测的技术方面。
Br J Cancer Suppl. 1973 Aug;1:229-36.
4
Macrophage electrophoretic migration (MEM) test for lymphocyte sensitization: some practical experiences in macrophage selection.用于淋巴细胞致敏的巨噬细胞电泳迁移(MEM)试验:巨噬细胞选择的一些实践经验
Br J Cancer Suppl. 1973 Aug;1:215-8.
5
Evaluation and development of the macrophage electrophoretic mobility (MEM) test for malignant disease.恶性疾病巨噬细胞电泳迁移率(MEM)检测的评估与开发。
Br J Cancer. 1973 Jan;27(1):1-9. doi: 10.1038/bjc.1973.1.
6
Lymphocyte sensitization in asthma with special reference to nature and identity of intrinsic form.哮喘中的淋巴细胞致敏,特别涉及内在形式的性质和特征。
Br Med J. 1973 Jan 6;1(5844):15-6. doi: 10.1136/bmj.1.5844.15.
7
[Macrophage electrophoretic migration test for lymphocyte sensitization to tumor antigens (author's transl)].用于检测淋巴细胞对肿瘤抗原致敏的巨噬细胞电泳迁移试验(作者译)
Tumori. 1974 May-Jun;60(3):203-10. doi: 10.1177/030089167406000305.
8
[Application and significance of macrophage-electrophoretic-mobility-test (MEM) in neurological diseases (author's transl)].巨噬细胞电泳迁移率试验(MEM)在神经系统疾病中的应用及意义(作者译)
Klin Wochenschr. 1974 May 15;52(6):288-92. doi: 10.1007/BF01468460.
9
The macrophage electrophoretic mobility (MEM) test for malignant disease. Further clinical investigations and studies on macrophage slowing factors.恶性疾病的巨噬细胞电泳迁移率(MEM)试验。关于巨噬细胞迟缓因子的进一步临床研究
Clin Exp Immunol. 1974 Dec;18(4):543-52.
10
Antigen cross-reactivity in the macrophage electrophoretic mobility test. A study using cellular affinity chromatography.巨噬细胞电泳迁移率试验中的抗原交叉反应性。一项使用细胞亲和层析的研究。
Clin Exp Immunol. 1974 May;17(1):103-11.