Werner H, Masihi K N, Tischer I, Adusu E
Tropenmed Parasitol. 1977 Dec;28(4):528-32.
A substantial reduction of brain cyst numbers could be obtained through a six week therapy with SDDS-pyrimethamine combination or a high titer anti-Toxoplasma serum. NMRI mice experimentally infected three months earlier with cyst-forming Toxoplasma strains Witting, Alt or Gail were used. The effectiveness of the treatments could be increased considerably by simultaneous administration of anti-Toxoplasma serum and SDDS-pyrimethamine. A highly significant reduction of brain cyst numbers, upto 65%, could be obtained by using this mode of chemoimmunotherapy. The effectiveness of the treatments used varied amongst the three Toxoplasma strains.
通过使用磺胺嘧啶-乙胺嘧啶组合或高滴度抗弓形虫血清进行六周治疗，可使脑囊肿数量大幅减少。使用的是三个月前经形成囊肿的弓形虫菌株Witting、Alt或Gail实验感染的NMRI小鼠。同时给予抗弓形虫血清和磺胺嘧啶-乙胺嘧啶可显著提高治疗效果。通过这种化学免疫疗法可使脑囊肿数量大幅减少，高达65%。所用治疗方法的效果在三种弓形虫菌株之间有所不同。
