Bergman L, Krause U
Scand J Gastroenterol. 1977;12(8):937-44. doi: 10.3109/00365527709181353.
A series of 186 patients with Crohn's disease treated during the period 1956--1968 was followed up. During the follow-up period about 95% of the patients had undergone resection or by-pass surgery. The patients operated on between 1956--1968 were followed up with reference to recurrence rate. The mean observation time was 10.5 years. The recurrence rate after resection was 51%. "Radical" resection gave 29% recurrences. "Non-radical" resection gave 84% recurrences. Patients who had undergone a primary "radical" resection needed fewer re-operations, had fewer recurrences and a better "quality of life" than patients with a "non-radical" first operation. The total mortality in operations or due to complications of Crohn's disease in the series was 5.4%. The mortality in connection with operations was 3.4%. The general health of the patients examined in 1975 (165 patients) was estimated; 87% were in very good general health, 9.1% had moderate subjective symptoms, and 3.6% had pronounced subjective symptoms.
对1956年至1968年期间接受治疗的186例克罗恩病患者进行了随访。在随访期间，约95%的患者接受了切除术或旁路手术。对1956年至1968年期间接受手术的患者进行了复发率随访。平均观察时间为10.5年。切除术后的复发率为51%。“根治性”切除术后复发率为29%。“非根治性”切除术后复发率为84%。与首次进行“非根治性”手术的患者相比，首次接受“根治性”切除术的患者再次手术的需求更少，复发次数更少，“生活质量”更高。该系列中手术或因克罗恩病并发症导致的总死亡率为5.4%。手术相关死亡率为3.4%。对1975年检查的患者（165例）的总体健康状况进行了评估；87%的患者总体健康状况非常好，9.1%的患者有中度主观症状，3.6%的患者有明显主观症状。
