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6至18岁哮喘儿童中两剂次二价甲型流感疫苗的多中心试验。

Multicenter two-dose trials of bivalent influenza A vaccines in asthmatic children aged six to 18 years.

作者信息

McIntosh K, Foy H, Modlin J F, Boyer K M, Hilman B C, Gross P A

出版信息

J Infect Dis. 1977 Dec;136 Suppl:S645-7. doi: 10.1093/infdis/136.supplement_3.s645.

DOI:10.1093/infdis/136.supplement_3.s645
PMID:606787
Abstract

Data from all of the vaccination centers that immunized asthmatic children six to 18 years old with bivalent influenza A/New Jersey/76 and A/Victoria/75 vaccines were analyzed. Systemic reaction indexes were somewhat higher in asthmatic children receiving the first dose of whole-virus vaccines than in similar vaccinees without asthma. Antibody levels after immunization, while different in some instances, did not show any significant trends toward either hypo- or hyperresponsiveness in the asthmatic children.

摘要

对所有为6至18岁哮喘儿童接种二价甲型流感疫苗(新泽西/76株和维多利亚/75株)的疫苗接种中心的数据进行了分析。接受首剂全病毒疫苗的哮喘儿童的全身反应指标略高于无哮喘的类似接种者。免疫后的抗体水平在某些情况下有所不同,但在哮喘儿童中未显示出任何显著的低反应性或高反应性趋势。

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Multicenter two-dose trials of bivalent influenza A vaccines in asthmatic children aged six to 18 years.6至18岁哮喘儿童中两剂次二价甲型流感疫苗的多中心试验。
J Infect Dis. 1977 Dec;136 Suppl:S645-7. doi: 10.1093/infdis/136.supplement_3.s645.
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