Maury C P
Rheumatol Int. 1984;5(1):1-7. doi: 10.1007/BF00541358.
Recent advances in amyloid research have broadened our understanding of amyloidogenesis in connection with chronic inflammatory and infectious conditions. Experimental and clinical studies have clarified many of the mechanisms of induction, synthesis and regulation of the amyloid-related serum component SAA and have shed light on the enzymatic processes involved in the cleavage of SAA and degradation of fibrillar AA protein. The current pathogenetic model emphasizes the dynamic character of amyloid disease.
淀粉样蛋白研究的最新进展拓宽了我们对与慢性炎症和感染性疾病相关的淀粉样蛋白生成的理解。实验和临床研究阐明了淀粉样蛋白相关血清成分SAA的诱导、合成和调节的许多机制，并揭示了SAA裂解和纤维状AA蛋白降解所涉及的酶促过程。当前的发病机制模型强调了淀粉样蛋白疾病的动态特征。
