Fields P I, Schreier H J, Saha A L, Bernlohr R W
J Bacteriol. 1984 Aug;159(2):803-4. doi: 10.1128/jb.159.2.803-804.1984.
The isolation of auxotrophic mutants of Bacillus licheniformis, a microbe containing constitutive beta-lactamase activity, was found to be facilitated by the addition of clavulanic acid and cefotaxime during enrichment.
在地衣芽孢杆菌(一种含有组成型β-内酰胺酶活性的微生物)中,发现添加棒酸和头孢噻肟有助于在富集过程中分离营养缺陷型突变体。