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β-内酰胺酶抑制剂克拉维酸在地衣芽孢杆菌营养缺陷型突变体分离中的应用。

Use of the beta-lactamase inhibitor clavulanic acid in the isolation of auxotrophic mutants of Bacillus licheniformis.

作者信息

Fields P I, Schreier H J, Saha A L, Bernlohr R W

出版信息

J Bacteriol. 1984 Aug;159(2):803-4. doi: 10.1128/jb.159.2.803-804.1984.

DOI:10.1128/jb.159.2.803-804.1984
PMID:6086590
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC215723/
Abstract

The isolation of auxotrophic mutants of Bacillus licheniformis, a microbe containing constitutive beta-lactamase activity, was found to be facilitated by the addition of clavulanic acid and cefotaxime during enrichment.

摘要

在地衣芽孢杆菌(一种含有组成型β-内酰胺酶活性的微生物)中,发现添加棒酸和头孢噻肟有助于在富集过程中分离营养缺陷型突变体。

相似文献

1
Use of the beta-lactamase inhibitor clavulanic acid in the isolation of auxotrophic mutants of Bacillus licheniformis.β-内酰胺酶抑制剂克拉维酸在地衣芽孢杆菌营养缺陷型突变体分离中的应用。
J Bacteriol. 1984 Aug;159(2):803-4. doi: 10.1128/jb.159.2.803-804.1984.
2
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J Chemother. 1993 Jun;5(3):147-50. doi: 10.1080/1120009x.1993.11739223.
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Diagn Microbiol Infect Dis. 1987 Sep;8(1):61-5. doi: 10.1016/0732-8893(87)90049-6.
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引用本文的文献

1
Nitrogen catabolite repression of the L-asparaginase of Bacillus licheniformis.地衣芽孢杆菌L-天冬酰胺酶的氮代谢物阻遏
J Bacteriol. 1985 Nov;164(2):938-40. doi: 10.1128/jb.164.2.938-940.1985.
2
Nutrient-stimulated methylation of a membrane protein in Bacillus licheniformis.地衣芽孢杆菌中营养物质刺激的膜蛋白甲基化作用
J Bacteriol. 1988 Sep;170(9):4113-8. doi: 10.1128/jb.170.9.4113-4118.1988.

本文引用的文献

1
Large exopenicillinase, initial extracellular form detected in cultures of Bacillus licheniformis.大型外切青霉素酶,在地衣芽孢杆菌培养物中检测到的初始细胞外形式。
Biochemistry. 1980 Apr 29;19(9):1882-6. doi: 10.1021/bi00550a023.
2
beta-Lactamase stability of cefotaxime.头孢噻肟的β-内酰胺酶稳定性
J Antimicrob Chemother. 1980 Sep;6 Suppl A:13-7. doi: 10.1093/jac/6.suppl_a.13.
3
Pyruvate kinase of the spore-forming bacterium, Bacillus licheniformis. II. Kinetic properties.芽孢杆菌属的地衣芽孢杆菌的丙酮酸激酶。II. 动力学特性。
J Biol Chem. 1971 Mar 25;246(6):1746-55.
4
Clavulanic acid: a beta-lactamase-inhiting beta-lactam from Streptomyces clavuligerus.克拉维酸:一种来自棒状链霉菌的β-内酰胺酶抑制性β-内酰胺类抗生素。
Antimicrob Agents Chemother. 1977 May;11(5):852-7. doi: 10.1128/AAC.11.5.852.
5
HR 756, a new cephalosporin active against gram-positive and gram-negative aerobic and anaerobic bacteria.HR 756,一种对革兰氏阳性菌及革兰氏阴性需氧菌和厌氧菌均有活性的新型头孢菌素。
Antimicrob Agents Chemother. 1979 Feb;15(2):273-81. doi: 10.1128/AAC.15.2.273.
6
Determination of pools of tricarboxylic acid cycle and related acids in bacteria.细菌中三羧酸循环及相关酸的库的测定
Appl Environ Microbiol. 1977 Nov;34(5):512-7. doi: 10.1128/aem.34.5.512-517.1977.
7
Membrane-bound and secreted forms of penicillinase from Bacillus licheniformis.地衣芽孢杆菌青霉素酶的膜结合形式和分泌形式。
J Mol Biol. 1978 Dec 25;126(4):673-90. doi: 10.1016/0022-2836(78)90015-3.