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[病毒性肝炎血清学标志物的放射免疫学检测]

[Radioimmunological survey of serological markers of viral hepatitis].

作者信息

Gelosa L

出版信息

G Batteriol Virol Immunol. 1983 Jan-Jun;76(1-6):130-8.

PMID:6090251
Abstract

230 serum samples of HBsAg carriers have been investigated for the presence of the combination HBeAg/anti-HBe as an index infectivity: an infectivity titre of 5,65% has been found for HBeAg and a positivity titre of 83,04% for anti-HBe antibody. In the institutionalized patients of an isolated community the positive titre of HBeAg resulted 28,57% whilst in the relevant health care staff the positivity titre was the same as detected for the carriers mentioned above. In a episode of viral hepatitis A in a child community a serological survey for IgM anti-HAV revealed 8 asymptomatic positive individuals referable to exposure to A type virus: it proves the utility of the individuation of IgM anti-HAV for an early diagnosis of the viral infection.

摘要

对230份乙肝表面抗原(HBsAg)携带者的血清样本进行了研究,以检测HBe抗原/抗-HBe抗体组合作为感染性指标的情况:发现HBe抗原的感染性滴度为5.65%,抗-HBe抗体的阳性滴度为83.04%。在一个隔离社区的住院患者中,HBe抗原的阳性滴度为28.57%,而在相关医护人员中,阳性滴度与上述携带者检测结果相同。在一个儿童社区发生甲型病毒性肝炎疫情期间,针对IgM抗-HAV的血清学调查发现8名无症状阳性个体,提示曾接触A型病毒:这证明了IgM抗-HAV检测对于甲型病毒感染早期诊断的实用性。

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