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卡拉雅斯病毒和马拉巴病毒,两种从巴西白蛉中分离出的新型水疱性口炎病毒。

Carajas and Maraba viruses, two new vesiculoviruses isolated from phlebotomine sand flies in Brazil.

作者信息

Travassos da Rosa A P, Tesh R B, Travassos da Rosa J F, Herve J P, Main A J

出版信息

Am J Trop Med Hyg. 1984 Sep;33(5):999-1006. doi: 10.4269/ajtmh.1984.33.999.

DOI:10.4269/ajtmh.1984.33.999
PMID:6091472
Abstract

Two new rhabdoviruses, designated Carajas and Maraba, are described. Both were isolated from phlebotomine sand flies (Lutzomyia spp.) collected in the Amazon basin of Brazil. One recovery of Carajas virus was made from male sand flies. By complement-fixation and neutralization tests both agents were shown to be members of the vesicular stomatitis virus (VSV) serogroup (genus Vesiculovirus). The pathogenicity of the two viruses in mice and Vero cells is similar to that of VSV-Indiana and VSV-New Jersey. Both Carajas and Maraba viruses replicated in Lutzomyia longipalpis following intrathoracic inoculation, and both agents were transovarially transmitted in this sand fly species.

摘要

描述了两种新的弹状病毒,分别命名为卡拉雅斯病毒和马拉巴病毒。这两种病毒均从在巴西亚马逊盆地采集的白蛉(罗蛉属)中分离得到。从雄性白蛉中分离出了卡拉雅斯病毒。通过补体结合试验和中和试验表明,这两种病原体均为水疱性口炎病毒(VSV)血清群(水疱病毒属)的成员。这两种病毒在小鼠和Vero细胞中的致病性与VSV - 印第安纳株和VSV - 新泽西株相似。经胸腔接种后,卡拉雅斯病毒和马拉巴病毒均可在长须罗蛉体内复制,并且这两种病原体均可在该白蛉物种中经卵传递。

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