一所男子寄宿学校腺病毒3型感染暴发的调查。
Investigation of an outbreak of adenovirus type 3 infection in a boys' boarding school.
作者信息
Payne S B, Grilli E A, Smith A J, Hoskins T W
出版信息
J Hyg (Lond). 1984 Oct;93(2):277-83. doi: 10.1017/s0022172400064809.
Abstract
An outbreak of pharyngoconjunctival fever caused by adenovirus type 3 was studied in a boarding school for 800 boys aged 11-18 years. A total of 96 clinical cases were confirmed by laboratory tests. Clinical infection rates were higher in the younger boys but total infection rate did not vary with age. Previous infection provided 88% protection against reinfection. The techniques of virus isolation, complement fixation and neutralization were compared in the diagnosis of cases. Virus isolation diagnosed 86% of confirmed cases. Where acute sera (collected at onset) and convalescent sera (collected within one month) were available complement fixation and neutralization tests each diagnosed 96% of cases.
摘要
对一所招收800名11至18岁男生的寄宿学校中由3型腺病毒引起的咽结膜热暴发进行了研究。经实验室检测共确诊96例临床病例。年龄较小的男孩临床感染率较高，但总感染率不随年龄变化。既往感染可提供88%的再感染防护。对病例诊断中病毒分离、补体结合和中和技术进行了比较。病毒分离诊断出86%的确诊病例。在有急性期血清（发病时采集）和恢复期血清（发病后1个月内采集）的情况下，补体结合试验和中和试验各自诊断出96%的病例。
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