献血者巨细胞病毒抗体检测方法的评估

Assessment of methods for cytomegalovirus antibody testing of blood donations.

作者信息

Chung A, Chang W, Leung M K, Ofosu F A, Moore B P

出版信息

Vox Sang. 1984;47(5):343-7. doi: 10.1111/j.1423-0410.1984.tb04137.x.

DOI:10.1111/j.1423-0410.1984.tb04137.x

Abstract

As part of a programme to establish a panel of individuals with high titres of anticytomegalovirus (CMV) IgG for the production of CMV Ig, the CMV serostatus of 139 normal blood donors was determined by indirect haemagglutination assay, enzyme immunoassay, and complement fixation. The indirect haemagglutination assay was the most accurate and convenient method for the detection of CMV antibody negative donations. Plasma for production of hyperimmune CMV IgG could best be selected by an IgG-specific enzyme immunoassay procedure.

摘要

作为建立用于生产巨细胞病毒（CMV）免疫球蛋白的高滴度抗CMV IgG个体小组计划的一部分，通过间接血凝试验、酶免疫测定和补体结合试验对139名正常献血者的CMV血清状态进行了测定。间接血凝试验是检测CMV抗体阴性献血的最准确、最便捷的方法。用于生产高免疫CMV IgG的血浆最好通过IgG特异性酶免疫测定程序来选择。