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Cytomegalovirus (CMV) antibody in male homosexuals: a source for CMV immune globulin.

作者信息

Ikram H, Prince A M, Baker L N

出版信息

Vox Sang. 1983 Mar;44(3):173-7. doi: 10.1111/j.1423-0410.1983.tb01881.x.

DOI:10.1111/j.1423-0410.1983.tb01881.x
PMID:6301160
Abstract

Male homosexuals have been found to have an extraordinarily high prevalence, and high titers, of antibodies to cytomegalovirus (CMV), as determined by complement-fixation and passive hemagglutination tests. These findings support other data suggesting that CMV may be sexually transmitted. The high titers of CMV antibody found in this population suggest that the homosexual population may be a valuable source of plasma for preparations of CMV immune globulins. CMV immune globulins may be useful in passive immunoprophylaxis or immunotherapy in immunosuppressed patients.

摘要

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引用本文的文献

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Large-scale serological screening for cytomegalovirus antibodies in homosexual males by enzyme-linked immunosorbent assay.采用酶联免疫吸附测定法对男性同性恋者进行巨细胞病毒抗体的大规模血清学筛查。
J Clin Microbiol. 1984 Feb;19(2):200-3. doi: 10.1128/jcm.19.2.200-203.1984.
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Modulation of T- and B-lymphocyte functions by isoprinosine in homosexual subjects with prodromata and in patients with acquired immune deficiency syndrome (AIDS).异丙肌苷对有前驱症状的同性恋者及获得性免疫缺陷综合征(艾滋病)患者T淋巴细胞和B淋巴细胞功能的调节作用
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