• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

大鼠和兔子宫中γ-氨基丁酸(GABA)受体结合位点的鉴定

Identification of GABA receptor binding sites in rat and rabbit uterus.

作者信息

Erdó S L

出版信息

Biochem Biophys Res Commun. 1984 Nov 30;125(1):18-24. doi: 10.1016/s0006-291x(84)80327-7.

DOI:10.1016/s0006-291x(84)80327-7
PMID:6095837
Abstract

The present study provides evidence for the presence of gamma-aminobutyric acid (GABA) and L-glutamate decarboxylase in the uteri of the rat and the rabbit. Furthermore, it has been demonstrated for the first time that the uterine tissue contains high-affinity GABAA receptor binding sites in a high density. The present findings indicate that GABA may have a role in the uterine functions.

摘要

本研究为大鼠和家兔子宫中存在γ-氨基丁酸(GABA)和L-谷氨酸脱羧酶提供了证据。此外,首次证明子宫组织含有高密度的高亲和力GABAA受体结合位点。目前的研究结果表明,GABA可能在子宫功能中发挥作用。

相似文献

1
Identification of GABA receptor binding sites in rat and rabbit uterus.大鼠和兔子宫中γ-氨基丁酸(GABA)受体结合位点的鉴定
Biochem Biophys Res Commun. 1984 Nov 30;125(1):18-24. doi: 10.1016/s0006-291x(84)80327-7.
2
Gestational changes of GABA levels and GABA binding in the human uterus.人子宫中γ-氨基丁酸(GABA)水平及GABA结合的孕期变化
Life Sci. 1989;44(26):2009-14. doi: 10.1016/0024-3205(89)90346-9.
3
Identification of gamma-aminobutyric acid and its binding sites in Caenorhabditis elegans.秀丽隐杆线虫中γ-氨基丁酸及其结合位点的鉴定。
Life Sci. 1988;43(21):1701-6. doi: 10.1016/0024-3205(88)90481-x.
4
Pharmacological subtypes of the gamma-aminobutyric acidA receptors defined by a gamma-aminobutyric acid analogue 4,5,6,7-tetrahydroisoxazolo[5,4-c] pyridin-3-ol and allosteric coupling: characterization using subunit-specific antibodies.由γ-氨基丁酸类似物4,5,6,7-四氢异恶唑并[5,4-c]吡啶-3-醇定义的γ-氨基丁酸A受体的药理学亚型及变构偶联:使用亚基特异性抗体进行表征
Mol Pharmacol. 1995 Oct;48(4):666-75.
5
The effect of acute ethanol administration on GABA receptor binding in cerebellum and hypothalamus.急性给予乙醇对小脑和下丘脑γ-氨基丁酸(GABA)受体结合的影响。
Eur J Pharmacol. 1985 May 20;111(3):365-8. doi: 10.1016/0014-2999(85)90643-0.
6
A novel GABAA antagonist [3H]SR 95531: microscopic analysis of binding in the rat brain and allosteric modulation by several benzodiazepine and barbiturate receptor ligands.
Synapse. 1988;2(2):163-73. doi: 10.1002/syn.890020208.
7
Presence of gamma-aminobutyric acid and its specific receptor binding sites in the human term placenta.人足月胎盘γ-氨基丁酸及其特异性受体结合位点的存在。
Gynecol Obstet Invest. 1985;20(4):199-203. doi: 10.1159/000298994.
8
Immunohistochemical studies on distribution of GABAA receptor complex in the rat brain using antibody against purified GABAA receptor complex.使用抗纯化γ-氨基丁酸A型(GABAA)受体复合物抗体对大鼠脑内GABAA受体复合物分布进行的免疫组织化学研究。
Brain Res. 1989 Apr 3;483(2):395-401. doi: 10.1016/0006-8993(89)90187-x.
9
GABAA receptor subtypes: autoradiographic comparison of GABA, benzodiazepine, and convulsant binding sites in the rat central nervous system.GABAA受体亚型:大鼠中枢神经系统中GABA、苯二氮䓬和惊厥剂结合位点的放射自显影比较
J Chem Neuroanat. 1990 Jan-Feb;3(1):59-76.
10
Modulation of uterine GABAA receptors during gestation and by tetrahydroprogesterone.妊娠期及四氢孕酮对子宫GABAA受体的调节作用
Eur J Pharmacol. 1989 Dec 12;174(1):43-7. doi: 10.1016/0014-2999(89)90871-6.

引用本文的文献

1
Association between psychopharmacotherapy and postpartum hemorrhage.心理药物治疗与产后出血之间的关联。
AJOG Glob Rep. 2024 Oct 9;4(4):100402. doi: 10.1016/j.xagr.2024.100402. eCollection 2024 Nov.
2
Does the Act of Copulation per se, without Considering Seminal Deposition, Change the Expression of Genes in the Porcine Female Genital Tract?单纯的交配行为(不考虑精液沉积)是否会改变猪雌性生殖道内基因的表达?
Int J Mol Sci. 2020 Jul 31;21(15):5477. doi: 10.3390/ijms21155477.
3
Characteristic expressions of GABA receptors and GABA producing/transporting molecules in rat kidney.
大鼠肾脏中γ-氨基丁酸(GABA)受体及GABA产生/转运分子的特征性表达
PLoS One. 2014 Sep 4;9(9):e105835. doi: 10.1371/journal.pone.0105835. eCollection 2014.
4
Depletion of calcium stores contributes to progesterone-induced attenuation of calcium signaling of G protein-coupled receptors.钙库耗竭导致孕激素诱导的 G 蛋白偶联受体钙信号转导减弱。
Cell Mol Life Sci. 2010 Aug;67(16):2815-24. doi: 10.1007/s00018-010-0360-4. Epub 2010 Apr 8.
5
GABAA receptors are expressed and facilitate relaxation in airway smooth muscle.γ-氨基丁酸A型(GABAA)受体在气道平滑肌中表达并促进其舒张。
Am J Physiol Lung Cell Mol Physiol. 2008 Jun;294(6):L1206-16. doi: 10.1152/ajplung.00287.2007. Epub 2008 Apr 11.
6
Proceedings of the British Pharmacological Society. Nottingham, 7th-9th September 1988. Abstracts.英国药理学会会议记录。诺丁汉,1988年9月7日至9日。摘要
Br J Pharmacol. 1988 Dec;95 Suppl(Suppl):715P-910P.
7
Binding of [3H]-muscimol to GABAA sites in the guinea-pig urinary bladder: biochemical assay and autoradiography.[3H] - 蝇蕈醇与豚鼠膀胱中GABAA位点的结合:生化分析与放射自显影
Br J Pharmacol. 1989 Feb;96(2):313-8. doi: 10.1111/j.1476-5381.1989.tb11819.x.