Aniansson H, Stendahl O, Dahlgren C
Acta Pathol Microbiol Immunol Scand C. 1984 Dec;92(6):357-61. doi: 10.1111/j.1699-0463.1984.tb00100.x.
Phorbolmyristate acetate (PMA) induced both a luminol- and a lucigenindependent chemiluminescence response in normal polymorphonuclear leukocytes (PMNL). PMNL isolated from a patient with a myeloperoxidase (MPO)-deficiency were found to produce almost no luminol-dependent chemiluminescence. The lucigenin-dependent chemiluminescence response was, however, found not to differ between normal and MPO-deficient cells. From these results it was concluded that the luminol- and the lucigenin-dependent chemiluminescence differed in the dependence of MPO. Results obtained with cell-free MPO-H2O2- and superoxide anion producing systems further supported this conclusion.
佛波醇肉豆蔻酸酯乙酸盐（PMA）在正常多形核白细胞（PMNL）中诱导了鲁米诺依赖性和光泽精依赖性化学发光反应。从一名髓过氧化物酶（MPO）缺乏症患者分离出的PMNL几乎不产生鲁米诺依赖性化学发光。然而，发现正常细胞和MPO缺乏细胞之间的光泽精依赖性化学发光反应没有差异。从这些结果得出结论，鲁米诺依赖性和光泽精依赖性化学发光在对MPO的依赖性方面存在差异。用无细胞MPO-H2O2和超氧阴离子产生系统获得的结果进一步支持了这一结论。
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