de Felippe J, Timoner J, Velasco I T, Lopes O U, Rocha-e-Silva M
Lancet. 1980 Nov 8;2(8202):1002-4. doi: 10.1016/s0140-6736(80)92157-1.
Injections of hyperosmotic (7.5%) sodium chloride (100-400 ml) were given to 12 patients in terminal hypovolaemic shock who had not responded to vigorous volume replacement and corticosteroid and dopamine infusions. Hyperosmotic sodium chloride promptly reversed the shock in 11 of these patients. The immediate effects of the NaCl injections were a moderate rise in arterial pressure, the resumption of urine flow, and recovery of consciousness. These effects tended to persist for a few hours. The hyperosmotic infusion also reduced isosmotic fluid requirement by 90%.
对12例终末期低血容量性休克患者进行了高渗（7.5%）氯化钠注射液（100 - 400毫升）注射，这些患者对积极的容量复苏、皮质类固醇和多巴胺输注均无反应。高渗氯化钠迅速逆转了其中11例患者的休克状态。注射氯化钠后的即时效应是动脉压适度升高、尿流恢复以及意识恢复。这些效应往往持续数小时。高渗输注还使等渗液体需求量减少了90%。
