Wen H L
Comp Med East West. 1977 Fall-Winter;5(3-4):257-63. doi: 10.1142/s0147291777000362.
Detoxification can be accomplished more rapidly by first "flushing" the opiates from the receptor sites. Naloxone, a short acting antagonist displaces opiates from the receptor sites and such displacement precipitates an abstinence syndrome. Recently, a method of using acupuncture and electrical stimulation (AES) in combination with naloxone for fast detoxification was reported. This technique was applied to 50 cases of heroin addicts. Forty-one were detoxified. There were nine failures. Of the 41 cases, 18 patients were sent to rehabilitation centres and did not experience abstinence symptoms. Six were sent out of Hong Kong where heroin is not available, and two others did not go to a rehabilitation centre but still abstained. The other 15 were presumed to be on the drug. It is advocated that AES increases endorphin and relieves abstinence syndrome, but also at the same time inhibits the autonomic nervous system, mainly the parasympathetic nervous system. The technique does not stop the craving, therefore after detoxification, the patients should be sent for psycho-social rehabilitation, or alternatively be put on long acting antagonist.
通过首先将阿片类药物从受体部位“冲洗”出来,可以更快地完成脱毒。纳洛酮是一种短效拮抗剂,它能将阿片类药物从受体部位置换出来,这种置换会引发戒断综合征。最近,有报道称一种将针灸和电刺激(AES)与纳洛酮联合用于快速脱毒的方法。该技术应用于50例海洛因成瘾者。41例脱毒成功,9例失败。在41例中,18名患者被送往康复中心,未出现戒断症状。6名被送往没有海洛因的香港以外地区,另外2名未去康复中心但仍戒除了毒瘾。其他15名被推测仍在吸毒。有人主张,AES可增加内啡肽并缓解戒断综合征,但同时也会抑制自主神经系统,主要是副交感神经系统。该技术并不能消除对毒品的渴望,因此脱毒后,患者应被送去进行心理社会康复,或者使用长效拮抗剂。