Lerner T J, Zinder N D
J Bacteriol. 1982 Apr;150(1):156-60. doi: 10.1128/jb.150.1.156-160.1982.
We have examined the relationship between two chromosomal mutations of Escherichia coli K-12, fexA (0 min) and fexB (85 min), in regulating expression of the F sex factor. Together, fexA and fexB exert a pleiotropic effect on the expression of the F tra genes. F pilus synthesis, conjugal donor activity, and surface exclusion activity are all inhibited in the fexA fexB mutant. Either fex mutation alone is cryptic.
我们研究了大肠杆菌K-12的两种染色体突变fexA(0分钟)和fexB(85分钟)在调节F性因子表达方面的关系。fexA和fexB共同对F tra基因的表达产生多效性影响。在fexA fexB突变体中,F菌毛合成、接合供体活性和表面排斥活性均受到抑制。单独的任何一种fex突变都是隐性的。