Toggenburger G, Felix D, Cuénod M, Henke H
J Neurochem. 1982 Jul;39(1):176-83. doi: 10.1111/j.1471-4159.1982.tb04716.x.
The efflux of 20 amino acids, induced by either high K+ concentration or veratrine, was determined in pigeon tectal slices. Ca2+-dependent, K+-induced release of beta-alanine, gamma-aminobutyric acid (GABA), and glutamate was observed. Veratrine caused release of the same amino acids plus glycine in a tetrodotoxin-sensitive manner. beta-Alanine had a strong inhibitory effect on the activity of tectal neurons which was blocked by strychnine but not by bicuculline. The results indicated a transmitter function for beta-alanine in the optic tectum, and were consistent with the previously proposed transmitter role of GABA and glutamate in this structure.
在鸽子视顶盖切片中测定了由高钾浓度或藜芦碱诱导的20种氨基酸的外流。观察到钙离子依赖性的、钾离子诱导的β-丙氨酸、γ-氨基丁酸（GABA）和谷氨酸的释放。藜芦碱以对河豚毒素敏感的方式导致相同氨基酸以及甘氨酸的释放。β-丙氨酸对视顶盖神经元的活动有强烈的抑制作用，该作用被士的宁阻断，但不被荷包牡丹碱阻断。结果表明β-丙氨酸在视顶盖中具有递质功能，并且与先前提出的GABA和谷氨酸在该结构中的递质作用一致。
