Viola P L, Caputo A
Environ Health Perspect. 1977 Dec;21:45-7. doi: 10.1289/ehp.772145.
Results of a study on Wistar rats regarding a possible carcinogenic effect of vinylidene chloride (VDC) were presented previously by one of the authors. Due to the unclear character of these results, a second inhalation study was initiated with Sprague-Dawley rats. Groups of 60 animals were exposed to 100 and 75 ppm VDC, along with one control group. A final report on the pathological results must await completion of the microscopic examination of the tissues and organs from all the animals. Nevertheless, it seems clear that there is no grossly observable interrelation between tumor production and VDC inhalation.
一位作者之前曾介绍过一项关于Wistar大鼠的研究结果，该研究探讨了偏二氯乙烯（VDC）可能的致癌作用。由于这些结果的性质不明确，因此启动了第二项针对Sprague-Dawley大鼠的吸入研究。将60只动物分为几组，分别暴露于100 ppm和75 ppm的VDC环境中，同时设置一个对照组。关于病理结果的最终报告必须等待对所有动物的组织和器官进行显微镜检查完成之后才能得出。然而，似乎很明显，肿瘤产生与吸入VDC之间没有明显的可观察到的相互关系。
