工业级1,1,1-三氯乙烷中潜在致癌物的鉴定
Identification of potential carcinogens in technical grade 1,1,1-trichloroethane.
作者信息
Henschler D, Reichert D, Metzler M
出版信息
Int Arch Occup Environ Health. 1980;47(3):263-8. doi: 10.1007/BF00381683.
Gas chromatography and gas chromatography-mass spectrometry were employed to analyze 22 samples of technical grade 1,1,1-trichloroethane for impurities. Eighteen contained vinylidene chloride (1,1-dichloroethylene) (30-900 micrograms/ml) and further contaminants were identified as 1,1-dichloroethane (11), trichloroethylene (12), and 1,1,2-trichloroethane (9). Nitromethane (18), 1,2-epoxybutane (19), tert. butanol (7), and dioxane (10) were detected as stabilizers. It is recommended that the manufacturers should eliminate vinylidene chloride and stabilizers which carry a carcinogenic and/or mutagenic risk, from technical samples of 1,1,1-trichloroethane.
采用气相色谱法和气相色谱-质谱联用法对22个工业级1,1,1-三氯乙烷样品进行杂质分析。其中18个样品含有偏二氯乙烯（1,1-二氯乙烯）（30 - 900微克/毫升），另外还鉴定出其他污染物为1,1-二氯乙烷（11个样品）、三氯乙烯（12个样品）和1,1,2-三氯乙烷（9个样品）。检测到硝基甲烷（18个样品）、1,2-环氧丁烷（19个样品）、叔丁醇（7个样品）和二氧六环（10个样品）作为稳定剂。建议制造商从工业级1,1,1-三氯乙烷样品中去除具有致癌和/或致突变风险的偏二氯乙烯和稳定剂。
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