豚鼠肝脏发育过程中腐胺生成γ-氨基丁酸（GABA）的情况。
Gamma-aminobutyric acid (GABA) formation from putrescine in guinea-pig liver during ontogenesis.
作者信息
Fogel W A, Biegański T, Maśliński C
出版信息
Comp Biochem Physiol C Comp Pharmacol. 1982;73(2):431-4. doi: 10.1016/0306-4492(82)90148-4.
PMID:6129108
Abstract
- The changes in hepatic diamine oxidase (DAO) activity of the foetal and maternal origin and their relations to GABA formation during pregnancy in guinea-pigs are described. 2. Foetal DAO activity continuously increased while the maternal enzyme from the 45th day of gestation onwards decreased. 3. Conversion of putrescine to GABA via oxidative deamination has been detected in the earliest studied day i.e. the 34th.
摘要
- 本文描述了豚鼠孕期胎儿和母体来源的肝脏二胺氧化酶（DAO）活性变化及其与γ-氨基丁酸（GABA）形成的关系。2. 胎儿DAO活性持续增加，而母体酶活性从妊娠第45天起下降。3. 在最早研究的第34天就检测到了腐胺通过氧化脱氨转化为GABA的过程。
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