Schenker J G, Birkenfeld A, Schwartz S
Int J Gynaecol Obstet. 1982 Dec;20(6):455-61. doi: 10.1016/0020-7292(82)90006-6.
Epidemiological data on 1017 cases of primary cancer of endometrium in Israel diagnosed over a 7-year period are presented. Incidence of corpus cancer in Israel has not changed in the last decade; the mean incidence for the current study is 18.73/100,000 women above the age of 25. Eight percent of patients were above the age of 51, with a steep increase of incidence being found above the age of 35. Endometrial carcinoma was four to five times more prevalent in Jewish women of European-American origin than in those of Asian-African background. In 85% of the patients diagnosis was made while the disease was in Stage I. A strong correlation was found between endometrial cancer and infertility, but no correlation was found with diabetes and hypertension. The five-year survival rate in the present survey was 65.0%. Factors affecting prognosis and clinical stage of the disease at diagnosis, degree of myometrial invasion, tumor differentiation, age of the patient and type of treatment are discussed.
本文呈现了以色列在7年期间确诊的1017例子宫内膜原发性癌的流行病学数据。以色列子宫体癌的发病率在过去十年中没有变化；本研究的平均发病率为每10万名25岁以上女性中有18.73例。8%的患者年龄在51岁以上，35岁以上发病率急剧上升。欧美裔犹太女性子宫内膜癌的患病率是亚非裔背景女性的四到五倍。85%的患者在疾病处于I期时被确诊。子宫内膜癌与不孕症之间存在强相关性，但与糖尿病和高血压之间未发现相关性。本次调查的五年生存率为65.0%。讨论了影响预后的因素以及疾病诊断时的临床分期、肌层浸润程度、肿瘤分化、患者年龄和治疗类型。
