Sobel K G, McCart G M
Drug Intell Clin Pharm. 1983 Jul-Aug;17(7-8):539-42. doi: 10.1177/106002808301700708.
The relationship between nonenvironment-caused falls and drug use was evaluated in an intermediate care facility over a 14-month period. The medical problems and selected drug use of 45 patients who had fallen were retrospectively compared with those of a matched control population of 30 patients who had not fallen during this same period. Antihypertensives, diuretics, tranquilizers, sedative/hypnotics, antidepressants, and antianginal agents were reviewed for all patients. The use of diuretics, specifically furosemide, and sedative/hypnotics was significantly greater in the population who had fallen. Observations of dizziness, confusion, insomnia, and ataxia were recorded more frequently in that group, as well. Closer monitoring of medications, especially in specific drug classes, may help prevent accidental falls in this type of institution.
在一家中级护理机构中，对为期14个月的非环境因素导致的跌倒与药物使用之间的关系进行了评估。回顾性比较了45名跌倒患者与同期未跌倒的30名匹配对照人群的医疗问题和所选药物使用情况。对所有患者的抗高血压药、利尿剂、镇静剂、镇静/催眠药、抗抑郁药和抗心绞痛药进行了审查。跌倒人群中利尿剂（特别是呋塞米）和镇静/催眠药的使用明显更多。该组中头晕、意识模糊、失眠和共济失调的观察记录也更频繁。对药物进行更密切的监测，尤其是特定药物类别，可能有助于预防这类机构中的意外跌倒。
