Wells B G, Middleton B, Lawrence G, Lillard D, Safarik J
Drug Intell Clin Pharm. 1985 Feb;19(2):142-5. doi: 10.1177/106002808501900212.
In intermediate care facilities, the records of 41 patients who had fallen and 36 controls were reviewed retrospectively, and the two groups compared for demographics, diagnoses, blood pressures over the prior two months, and prescribed medication. Seven of the sample had a recent weight loss recorded; all seven were in the group that fell. The mean number of medications prescribed for the group of fallers was significantly greater than the mean prescribed for the control group. The mean number of medication changes during the two weeks prior to the fall was significantly greater than the mean number of medication changes during the two weeks prior to data collection for the control group. Our data suggest that caution should be exercised in multiple drug prescribing for patients in intermediate care facilities and that recent weight loss and medication changes may be risk factors for falling.
在中级护理机构中，对41名跌倒患者和36名对照者的记录进行了回顾性审查，并比较了两组的人口统计学、诊断情况、过去两个月的血压以及所开药物。样本中有7人近期有体重减轻记录；这7人都在跌倒组。跌倒组所开药物的平均数量显著高于对照组。跌倒前两周内药物变化的平均数量显著高于对照组数据收集前两周内药物变化的平均数量。我们的数据表明，在中级护理机构中为患者开多种药物时应谨慎，近期体重减轻和药物变化可能是跌倒的风险因素。
