Ruthazer R, Lipsitz L A
Hebrew Rehabilitation Center for Aged, Boston, MA 02131.
Am J Public Health. 1993 May;83(5):746-9. doi: 10.2105/ajph.83.5.746.
All eligible residents of a long-term care facility (488 women and 147 men with a 6-month minimum stay) were prospectively followed for 1 month for the development of falls. Use of psychotropic medications (excluding as needed prescriptions), functional status, and a history of falls were assessed at the start of the study month. Results of analyses using logistic modeling procedures suggest that institutionalized women on antidepressants may have an increased risk of falling, regardless of fall history, functional status, or age. A relationship between antidepressants and falls was not found for men. These results may help target high-risk individuals for future preventive efforts.
一家长期护理机构的所有符合条件的居民（488名女性和147名男性，至少入住6个月）被前瞻性地跟踪了1个月，以观察跌倒情况。在研究月开始时评估了精神药物的使用情况（不包括按需开具的处方）、功能状态和跌倒史。使用逻辑建模程序的分析结果表明，服用抗抑郁药的机构化女性可能跌倒风险增加，无论其跌倒史、功能状态或年龄如何。未发现男性抗抑郁药与跌倒之间存在关联。这些结果可能有助于确定未来预防工作的高危个体。
